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Walking through the mirror will teleport Isaac to the Mirrored world. Another room on the floor has a mirror, which Isaac can enter while a ghost. Touching the white fire place temporarily transforms Isaac into The Lost.
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The Wafer: Complete the full game 7 times. The Shears: I've lost my head one too many times. The Robo-Baby: Complete the full game with Judas. The Radioactive Spider: Complete the basement. The Quarter: Complete the full game 4 times. The Parasite: Kids shouldn't play with dead things. The Necronomicon: Call death upon all of them! The Noose: Complete the full game 2 times. The Halo: Give mom a taste of her own medicine! The Nail: Complete the full game 3 times. The Fetus: Complete the full game 5 times. The Cross: Complete the full game with Maggy. The Book of Sin: Destroy the 7 Sins! The Common Cold: Dirty needles. The Bandage: Make a Super Meat Boy! The Bean: You don't wanna know where this bean has been. The Bag: Complete the full game with Cain. My head hurts.: You defeated Steven! Spelunker Boy: Complete the caves without taking damage. Monstros Tooth: Defeat all bosses in the basement. Money = Power: Complete the full game 8 times. Moms Contact: Stay out of moms things! Moms Pill Bottle: Mom needs her pills! donate blood. Mamas Boy: Complete the full game without taking damage. Maggys Wig: Collect 7+ container hearts in one play through. Lokis Horns: Defeat all bosses in the depths. Lil Chubby: Defeat all bosses in the caves. I need a hug.: You defeated C.H.A.D.! It Lives!: Complete the full game 9 times. I have sticker fingers.: You defeated Gish! I Killed Mom!: Kill mom. Everything's Terrible!: Complete the full game 6 times. Dark Boy: Complete the depths without taking damage. Cain's Eyepatch: Collect 50+ pennies in one play through. Basement Boy: Complete the basement without taking damage. To view your achievements and stats in Steam, select "Community", "My profile", "View all my games", then the game and view stats. Successfully complete the indicated task to unlock the corresponding achievement. In the "Wrath Of The Lamb" downloadable content, defeat Mom and skip two treasure chest rooms to unlock Samson. Have seven heart containers in one playthrough to unlock Magdalene. Successfully complete the game two times to unlock Judas. Make two deals with the Devil in one playthrough. Have all 55 pennies at the same time in one playthrough to unlock Cain. Defeat It Lives by completing the game ten times to unlock ?.
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